실버 무기 항균제가 적용된 치과용 복합레진의 평가
Evaluation of Dental Composite Dispersed with Silver Inorganic Antibacterial Agent
문호진,
소속 상세정보
문호진 ( Moon Ho-Jin ) - 단국대학교 조직재생공학연구소
KMID : 0362220120390010049
Abstract
실버 무기 항균제인 Novaron과 INC-ZRS를 치과용 복합레진에 적용하여 굴곡/압축 강도, 중합심도/중합전환률, S. mutan 억제 능력을 확인하였다. 무기 항균제의 첨가는 강도와 중합전환율을 변화시키지 않았으나 INC-ZRS의 경우 중합심도를 떨어뜨렸다. S. mutans의 억제 능력 평가 결과, 모든 실험군에서 무기 항균제의 첨가로 순수한 복합레진보다 유의하게 높은 항균효과를 확인하였다(p<0.05).
The purpose of this study was to investigate the antibacterial effect of inorganic-silver particle on the conventional dental composite. Two antibacterial silver particles (Novaron and INC-ZRS) and silica were adopted to the filler system. A visible light system of camphorquinone photo-initiator and 2-(dimethylamino)ethyl methacrylate photo-accelerator was utilized to activate the resin matrix in the polymer composites. The degree of conversion, depth of cure, mechanical strength and antibacterial properties of dental composites were investigated. Two silver antibacterial agents could inhibit the growth of the major oral pathogen Streptococcus mutans. There was no significant difference in mechanical strength. However, there was a significant decrease in depth of cure for the INC-ZRS group. These results indicate that a dental resin composite incorporating silver antibacterial agent may be useful clinically because of its inhibitory effect against Streptococcus mutans and its favorable mechanical properties. Further study should be done to overcome the color instability and to demonstrate the biological stability.
키워드
Antibacterial agent; Dental composite; Inorganic-silver particle; Streptococcus metans
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